Significance of interleukin 17-A expression in colorectal cancer and adenoma
نویسندگان
چکیده
منابع مشابه
Prognostic significance of interleukin 17 in cancer: a meta-analysis.
The prognostic value of Interleukin 17 (IL-17) in cancer patients is currently under debate and remains inconclusive. We performed a systematic review and meta-analysis to evaluate the role of IL-17 as a prognostic marker in cancer. Hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) were combined to measure the effective value of IL-17 expression on prognosis. Nineteen eligibl...
متن کاملClinical significance of serum interleukin-17 levels in colorectal cancer patients.
PURPOSE The proinflammatory cytokine, interleukin-17 (IL-17) plays a potent role in T-cell mediated angiogenesis and promotes tumorigenicity. The objective of this study was to determine the clinical outcomes of colorectal cancer (CRC) patients in relation to serum IL-17 levels. METHODS Ninety-six CRC patients were enrolled in this study. Pre-treatment serum IL-17 levels were determined by en...
متن کاملInterleukin-17: A Promoter in Colorectal Cancer Progression
It is widely accepted that chronic inflammation plays an active role in cancer. Inflammatory immunocytes and related cytokines in the tumor microenvironment are supposed to be a "double-edged sword" in colorectal cancer (CRC) initiation and progression. Interleukin-17 (IL-17), a pleiotropic proinflammatory cytokine, can promote cancer-elicited inflammation and prevent cancer cells from immune s...
متن کاملClinicopathological significance of overexpression of interleukin-6 in colorectal cancer
AIM To compare the expression levels of interleukin (IL)-6 in colorectal cancer (CRC) tissues and adjacent non-cancerous tissues, and analyse the correlation of IL-6 expression with the clinicopathological parameters of CRC. METHODS Fifty CRC tissue specimens and 50 matched adjacent mucosa specimens were collected. The expression of IL-6 in these clinical samples was examined by immunohistoch...
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Introduction: Breast cancer is one of the inflammatory diseases, and physical inactivity is one of the risk factors. It has been suggested that exercise training can improve breast cancer outcomes by modulating inflammation. The aim of this study was to determine the effect of 12 weeks of high-intensity interval training and moderate- intensity continuous training on serum levels of IL-17 and I...
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ژورنال
عنوان ژورنال: World Chinese Journal of Digestology
سال: 2013
ISSN: 2219-2859
DOI: 10.11569/wcjd.v21.i25.2522